Linearized Vpr, Tat, E1A, p300 and CtBP1 molecules as well as their mutual interaction domains. Vpr interacts with GR and a number of other other NRs by its LxxLL motif Situated at amino acids 64 to 69. Binding web-sites of Vpr and p160-form HAT coactivators overlap with each other on p300. Since Vpr has a LxxLL motif comparable to p160 coactivator… Read More